Degradable poly(vinyl alcohol) hydrogels

Details Degradable poly(vinyl alcohol) hydrogels Degradable poly(vinyl alcohol) hydrogels

C - Chemistry, Metallurgy

08

F

C08F 8/00 (2006.01) A61L 15/24 (2006.01) A61L 15/64 (2006.01) A61L 27/16 (2006.01) A61L 27/52 (2006.01) A61L 27/58 (2006.01) A61L 31/04 (2006.01) A61L 31/14 (2006.01) C08F 8/12 (2006.01) C08F 261/04 (2006.01) C08F 283/00 (2006.01) C08L 51/00 (2006.01)

Patent

CA 2391618

Biodegradable biocompatible hydrogels based on poly(vinyl alcohol) and methods for their preparation. The methods for preparation of the hydrogels involve the use of prepolymers. The prepolymers have a PVA backbone and pendant chains that include a polymerizable group. In one embodiment, the pendant chains also include a biodegradable region. In another embodiment, biodegradable regions are incorporated into the hydrogel during formation.

L'invention concerne des hydrogels biocompatibles biodégradables à base d'alcool polyvinylique et des procédés de préparations associés. Les procédés de préparation des hydrogels impliquent l'utilisation de prépolymères. Les prépolymères possèdent un squelette polyvinylique et des chaînes greffées comprenant un groupe polymérisable. Dans l'un des modes de réalisation, les chaînes greffées comprennent également une zone biodégradable. Dans un autre mode de réalisation, les zones biodégradables sont introduites dans l'hydrogel au cours de sa formation.

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