A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61K 38/46 (2006.01) A61K 38/47 (2006.01) A61K 38/51 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2525782
This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including proteoglycan degrading molecules and compositions capable of blocking and/or over coming the activity of neuronal growth inhibitory molecules, as well as fusion proteins which includes a proteoglycan degrading domain and a domain capable of blocking and or over coming the activity of neuronal growth inhibitory molecules.
L'invention concerne des compositions pouvant être utilisées dans le traitement de lésions de la moelle épinière et de troubles associés du système nerveux central (SNC), et plus particulièrement des compositions comprenant des molécules de dégradation du protéoglycane et des compositions permettant de bloquer et/ou de supprimer l'activité de molécules inhibitrices de la croissance neuronale, ainsi que des protéines de fusion renfermant un domaine de dégradation du protéoglycane et un domaine permettant de bloquer et/ou de supprimer l'activité de molécules inhibitrices de la croissance neuronale.
Caggiano Anthony O.
Gruskin Elliott A.
Iaci Jennifer
Roy Gargi
Zimber Michael P.
Acorda Therapeutics Inc.
Borden Ladner Gervais Llp
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