Dehydroxylation of aminoglycosides

Details Dehydroxylation of aminoglycosides Dehydroxylation of aminoglycosides

C - Chemistry, Metallurgy

07

H

260/230

C07H 15/22 (2006.01) C07H 15/23 (2006.01) C07H 15/232 (2006.01) C07H 15/236 (2006.01)

Patent

CA 1061337

DEHYDROXYLATION OF AMINOGLYCOSIDES Abstract of the Disclosure Deoxyaminoglycoside antibiotics are prepared in a high yield from phosphorylated aminoglycoside by reacting a phosphorylated aminoglycoside (a) with a silylating agent, or (b) successively with (i) a silylating or acylating agent and (ii) a halogenating agent; then subjecting thus obtained intermediate to reduction. Deoxyaminoglycoside antibiotics are useful for treating infections caused by microorganisms which are resistant or non-resistant to the corresponding aminoglycoside antibiotics.

224249

Affiliated with

Also associated with

Rating

Dehydroxylation of aminoglycosides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dehydroxylation of aminoglycosides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dehydroxylation of aminoglycosides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-505616