Delayed release pharmaceutical formulations

Details Delayed release pharmaceutical formulations Delayed release pharmaceutical formulations

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/22 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2433186

Delivery of a drug is controlled to impart a delay before release after administration by formulating the drug with a disruption agent to provide a core, and coating the core with a regulatory membrane comprising a water- soluble gel-forming polymer and a water-insoluble film-forming polymer.

Selon cette invention, la libération d'un médicament est commandée pour conférer un retard avant la libération après l'administration, par préparation du médicament avec un agent de rupture pour former un élément central, et par revêtement de cet élément central à l'aide d'une membrane régulatrice comprenant un polymère gélifiant hydrosoluble et un polymère filmogène insoluble dans l'eau.

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