Delayed release tablet with defined core geometry

Details Delayed release tablet with defined core geometry Delayed release tablet with defined core geometry

A - Human Necessities

61

K

A61K 9/28 (2006.01) A61K 9/00 (2006.01) A61K 9/30 (2006.01) A61K 9/36 (2006.01) A61K 31/573 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2523158

A press-coated tablet comprising a core containing an drug substance, and a coating, the core being disposed within the coating such that the coating has a first thickness about an axis A-B and a thickness about an orthogonal axis X- Y, such that the coating about the axis X-Y is thicker than the coating about the axis A-B, and is adapted to provide a lag time of between about 2 to 6 hours during which substantially no drug substance is released.

Double comprimé comportant un noyau contenant une substance médicamenteuse et un enrobage, le noyau étant disposé à l'intérieur de l'enrobage de telle sorte que ce dernier présente une première épaisseur autour d'un axe A-B et une épaisseur autour d'un axe orthogonal X-Y, l'épaisseur de l'enrobage autour de l'axe X-Y étant supérieure à son épaisseur autour de l'axe A-B. Ce comprimé est conçu pour présenter un temps de latence d'environ 2 à 6 heures au cours duquel il ne libère sensiblement pas de substance médicamenteuse.

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