Deletion mutants for the production of isobutanol

Details Deletion mutants for the production of isobutanol Deletion mutants for the production of isobutanol

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) C12N 9/04 (2006.01) C12P 7/16 (2006.01)

Patent

CA 2723874

An E. coli host strain was engineered wherein genes adhE, ldhA, frdB, and pflB were disrupted and novel butanol dehydrogenase gene, sadB, from Achromobacter xylosoxidans, was added to produce the isobutanol production host.

Selon linvention, une souche hôte d'E. coli a été synthétisée par génie génétique, les gènes adhE, ldhA, frdB et pflB ayant été rompus et un nouveau gène de la butanol déshydrogénase, sadB, provenant d'Achromobacter xylosoxidans, ayant été ajouté pour produire l'hôte de production d'isobutanol.

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