A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/00 (2006.01) A61K 38/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2735421
The invention relates to the use of a CD40 agonist for treating cancer, a pre- malignant disorder or an infectious disease, wherein a CD40 agonist is locally administered and targeted to a tumor draining lymph node of a subject. Optionally, a CD40 agonist is formulated in a slow--release formulation. Optionally, a CTL-activating peptide is further administered.
La présente invention concerne lutilisation dun agoniste de CD40 pour traiter un cancer, un trouble prémalin ou une maladie infectieuse, où un agoniste de CD40 est administré localement et ciblé sur un ganglion lymphatique drainant une tumeur dun sujet. Éventuellement, un agoniste de CD40 est formulé dans une formulation à libération lente. Éventuellement, un peptide activant CTL est également administré.
Herbert-Fransen Marieke Fernande
Melief Cornelis Joseph Maria
Academisch Ziekenhuis Leiden H.o.d.n. Lumc
Blake Cassels & Graydon Llp
LandOfFree
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