Delivery of active agents

Details Delivery of active agents Delivery of active agents

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 31/495 (2006.01) A61K 38/26 (2006.01)

Patent

CA 2703234

A method of introducing a physiologically-active agent into the circulatory system of a mammal is disclosed herein. The method utilizes a rapid drug delivery system which prevents deactivation or degradation of the active agent being administered to a patient in need of treatment. In particular, the drug delivery system is designed for pulmonary drug delivery such as by inhalation, for delivery of the active agents such as proteins and peptides to the pulmonary circulation in a therapeutically effective manner avoiding degradation of the active agents in peripheral and vascular tissue before reaching the target site.

La présente invention concerne un procédé d'introduction d'un agent physiologiquement actif dans le système circulatoire d'un mammifère. Ledit procédé utilise un système d'administration rapide de médicament qui empêche la désactivation ou la dégradation de l'agent actif administré à un patient ayant besoin d'être traité. En particulier, le système d'administration de médicament est conçu pour une administration pulmonaire, par exemple par inhalation ; ce système vise à fournir les agents actifs - tels que des protéines et des peptides - dans la circulation pulmonaire d'une manière thérapeutiquement efficace qui évité la dégradation des agents actifs dans les tissus périphériques et vasculaires avant d'atteindre le site cible.

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