Delivery of agents

Details Delivery of agents Delivery of agents

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 8/66 (2006.01) A61K 38/44 (2006.01) A61Q 11/00 (2006.01) C07K 16/42 (2006.01)

Patent

CA 2052713

An antibody fragment able to bind to a target site is prolonged by an additional peptide. The therapeutic agent is bound to this peptide or means are provided to bring about such binding. The antibody fragment and possibly also the therapeutic agent are included in a product so that binding to the target site delivers the therapeutic agent to the vicinity. The product may for example be for dental care, such as a toothpaste or mouthwash and the antibody fragment may then bind to a component of dental plaque.

Un fragment d'anticorps pouvant se lier à un site cible est prolongé par un peptide complémentaire. L'agent thérapeutique est lié à ce peptide, ou des moyens sont prévus pour effectuer cette liaison. Le fragment d'anticorps et peut-être aussi l'agent thérapeutique sont présents dans un produit, de telle façon que le site cible libère l'agent thérapeutique à proximité. Le produit peut par exemple servir à l'hygiène dentaire, comme dans un dentifrice ou un rince-bouche, et le fragment d'anticorps peut ensuite se fixer à un constituant de plaque dentaire.

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