Delivery of microparticle formulations using needleless...

A - Human Necessities – 61 – K

Patent

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A61K 9/16 (2006.01) A61M 5/30 (2006.01)

Patent

CA 2364198

A composition for administration to a subject by means of a needleless syringe comprises particles which have a mean mass aerodynamic diameter of from 1 to 250 microns and an envelope density of from 0.1 to 25 g/cm3, the particles comprising a biologically active agent and a sustained-release material which controls the release of the active agent to the subject following administration.

L'invention concerne une composition à administrer à un sujet à l'aide d'une seringue sans aiguille renfermant des particules dont le diamètre aérodynamique massique moyen oscille entre 1 et 250 microns et dont la densité de l'enveloppe oscille entre 0,1 et 25 g/cm?3¿, les particules comprenant un agent biologiquement actif et une substance à libération lente régulant la libération de l'agent actif.

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