Delivery of multiple genes to cells using plural...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) C12N 15/85 (2006.01) C12N 15/864 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2316321

A method for transducing a polypoid, multinucleate or polysomic cell with plural rAAVs carrying different transgenes. A suitable cell is a striated muscle cell or hepatocyte.

Procédé de transduction d'une cellule polypoïde, multinuclée ou polysomique au moyen de plusieurs vecteurs viraux adéno-associés de recombinaison (rAAVs) portant différents transgènes. Une cellule appropriée consiste en une cellule de muscle strié ou en une cellule hépatique.

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