A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/34 (2006.01) A61K 9/10 (2006.01) A61P 27/02 (2006.01) A61M 31/00 (2006.01)
Patent
CA 2649672
The present invention provides intraocular polymer delivery compositions based on biodegradable polyester amide (PEA), polyester urethane (PEUR), and polyester urea (PEU) polymers, which contain amino acids. The compositions can be formulated as an implantable solid or as a liquid dispersion of polymer particles for sustained delivery of ophthalmologic agents dispersed therein or incorporated into the backbone of the polymers. Methods of delivering an ophthalmologic agent to the exterior or interior of the eye by implanting the composition in the eye of a subject are also included.
L'invention concerne des compositions polymères intraoculaires d'administration médicamenteuse à base de polymères biodégradables polyester-amide (PEA), polyester-uréthane (PEUR) et polyester-urée (PEU), qui contiennent des acides aminés. Les compositions de l'invention peuvent être formulées sous la forme d'une dispersion solide implantable ou d'une dispersion liquide de particules polymères permettant la libération prolongée d'agents ophtalmiques dispersés ou incorporés au squelette des polymères. L'invention se rapporte également à des procédés permettant d'administrer un agent ophtalmique à l'extérieur ou à l'intérieur d'un oeil en implantant la composition dans l'oeil d'un sujet.
Landis Geoffrey C.
Turnell William D.
Yumin Yuan
Medivas Llc
Smart & Biggar
LandOfFree
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