Delivery of polypeptide-encoding plasmid dna into the...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/87 (2006.01) A61K 31/70 (2006.01) A61K 39/00 (2006.01) C12N 1/21 (2006.01) C12N 15/74 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2317111

The invention relates to the introduction of DNA or RNA sequences into a mammalian cell to achieve controlled expression of a polypeptide. It is therefore useful in gene therapy, vaccination, and any therapeutic situation in which a polypeptide should be administered to a host or cells of said host, as well as for the production of polypeptides by mammalian cells, e.g., in culture or in transgenic animals.

L'invention concerne l'introduction de séquences d'ADN ou d'ARN dans une cellule de mammifère afin de contrôler l'expression d'un polypeptide. Cette invention est donc utile pour la thérapie génique, la vaccination et toutes les situations thérapeutiques dans lesquelles on veut administrer un polypeptide à un hôte ou à des cellules dudit hôte, ainsi que pour la production de polypeptides par des cellules de mammifère, en culture ou chez des animaux transgéniques par exemple.

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