Delivery system controlled through factors associated with...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/85 (2006.01) A61K 38/45 (2006.01) A61K 48/00 (2006.01) C07K 14/16 (2006.01) C07K 14/61 (2006.01) C07K 14/705 (2006.01) C07K 14/805 (2006.01) C12N 5/10 (2006.01) C12N 15/867 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2158252

A method is disclosed for the preven- tion or treatment of a viral infection com- prising administering to a subject an effec- tive amount of a delivery system comprising a vector effective to express in a cell sus- ceptible to infection by the virus a gene en- coding an agent which is effective, directly or indirectly, to prevent, eliminate or attenu- ate the infection, wherein the gene is subject to control between an operative state and an inoperative state in the cell through factors specifically associated with the virus and the cell. The method of the invention allows the effective regulation of gene products in tar- get cells.

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