A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 47/32 (2006.01) A61L 31/04 (2006.01) A61L 31/16 (2006.01) A61M 31/00 (2006.01)
Patent
CA 2670454
This invention relates to an extended release formulation comprising a solid non-steroidal non-ionized hydrophilic drug, having a molecular weight below 500 Dalton and having a solubility of at least 0.1 wt% in ethylene vinyl acetate copolymer having a vinyl acetate content of 28%, which formulation is a vaginal device having a skin and which device comprises an inner compartment made of a thermoplastic polymer, which polymer is containing the drug. The polymer is preferably made of ethylene-vinyl acetate copolymer.
L'invention concerne une formulation à libération prolongée contenant un médicament hydrophile non stéroïdien non ionisé présentant un poids moléculaire inférieur à 500 Daltons et une solubilité d'au moins 0,1% en poids dans un copolymère d'éthylène-acétate de vinyle avec un contenu d'acétate de vinyle de 28%. Ladite formulation est un dispositif vaginal revêtu d'une enveloppe et comprenant un compartiment fait d'un polymère thermoplastique contenant le médicament. Le polymère est fait, de préférence, d'un copolymère d'éthylène-acétate de vinyle.
de Graaff Wouter
Szegedi Armin
Fetherstonhaugh & Co.
N.v. Organon
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