Delivery system for entrapping charged macromolecules and a...

Details Delivery system for entrapping charged macromolecules and a... Delivery system for entrapping charged macromolecules and a...

A - Human Necessities

61

K

A61K 9/107 (2006.01)

Patent

CA 2426967

The present invention relates to a new delivery system and method for producing same. The delivery system is a biphasic system of delivering charged macromolecules and comprises a negatively charged hydrophobic organic phase and a positively charged inorganic phase. The organic phase and the inorganic phase entrapping added macromolecules. The macromolecules are entrapped by electrostatic bonds between the organic phase, the inorganic phase and the macromolecules. The method for producing the delivery system comprises the steps of contacting together and mixing a negatively charged organic phase, a charged macro-molecule and positively charged inorganic phase.

Cette invention se rapporte à un nouveau système d'administration et à un procédé de production de ce système. Ce système d'administration est constitué par un système biphasique d'administration de macromolécules chargées et contient une phase organique hydrophobe chargée négativement et une phase inorganique chargée positivement. La phase organique et la phase inorganique encapsulent les macromolécules ajoutées. Les macromolécules sont encapsulées par les liaisons électrostatiques présentes entre la phase organique, la phase inorganique et les macromolécules. Le procédé de production de ce système d'administration consiste à mettre en contact et à mélanger une phase organique chargée négativement, une macromolécule chargée et une phase inorganique chargée positivement.

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