C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/87 (2006.01) A61K 9/107 (2006.01) A61K 9/50 (2006.01) A61K 48/00 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2410052
The invention features a composition for the delivery of bioactive agents into cells that includes a delivery matrix, an anionic or zwitterionic compound, and a bioactive agent, e.g. a peptide, protein, or nucleic acid. The compositions of the invention can be used to deliver bioactive compounds, such as nucleic acids encoding immunostimulatory peptides and/or therapeutic proteins.
La présente invention concerne une composition de distribution d'agents bioactifs dans les cellules, comprenant une matrice de distribution, un composé anionique ou zwitterionique, et un agent bioactif, par exemple, un peptide, une protéine, ou un acide nucléique. On peut utiliser ces compositions pour administrer des composés bioactifs, notamment des acides nucléiques codant des peptides immunostimulateurs et/ou des protéines thérapeutiques.
Barman Shikha P.
Hedley Mary Lynne
Mckeever Una
Eisai Inc.
Smart & Biggar
Zycos Inc.
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