C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/88 (2006.01) A61K 9/127 (2006.01) A61K 31/70 (2006.01) A61K 47/44 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2220950
Stable polynucleotide delivery vehicles (SPDVs) are described which incorporate a polynucleotide/cationic lipid complex as structural components of the SPDV. The subject SPDVs may optionally incorporate synthetic biodegradable amphipathic lipids, and suitable targeting agents.
L'invention a pour objet des véhicules d'apport de polynucléotides stables (SPDV) qui contiennent, comme éléments structuraux, un complexe polynucléotidique/lipides cationiques. Les SPDV de l'invention peuvent éventuellement comprendre des lipides amphipatiques biodégradables de synthèse, et des agents de ciblage adéquats.
Hofland Hans
Sullivan Sean M.
Cell Genesys Inc.
Gowling Lafleur Henderson Llp
Somatix Therapy Corporation
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