C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) C12N 1/14 (2006.01) C12N 15/74 (2006.01) C12P 21/06 (2006.01)
Patent
CA 2542574
The present invention relates to fungal .DELTA.-15 fatty acid desaturases that are able to catalyze the conversion of linoleic acid (18:2, LA) to alpha- linolenic acid (18:3, ALA). Nucleic acid sequences encoding the desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising the desaturase genes, and recombinant host plants and microorganisms expressing increased levels of the desaturases are described. Methods of increasing production of specific omega-3 and omega-6 fatty acids by over- expression of the .DELTA.-15 fatty acid desaturases are also described herein.
L'invention concerne des .DELTA.-15 désaturases d'acides gras fongiques susceptibles de catalyser la conversion d'acide linoléique (18:2, LA) en acide .alpha.-linolénique (18:3, ALA). L'invention concerne des séquences d'acides nucléiques codant les désaturases, des séquences d'acides nucléiques qui s'hybrident avec les précédentes, des constructions d'ADN comprenant les gènes désaturases, et des plantes hôtes de recombinaison et micro-organismes exprimant des niveaux accrus des désaturases. L'invention concerne en outre des procédés permettant d'accroître la production d'acides gras oméga-3 et oméga-6 spécifiques par surexpression des .DELTA.-15 désaturases d'acides gras.
E.i. Du Pont de Nemours And Company
Torys Llp
LandOfFree
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