Delta 6-desaturase genes and uses thereof

Details Delta 6-desaturase genes and uses thereof Delta 6-desaturase genes and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 9/02 (2006.01) A01H 5/00 (2006.01) A61P 3/02 (2006.01) C12N 15/52 (2006.01) C12P 7/64 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2578049

The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 6 (i.e., ".DELTA.6- desaturase"). In particular, .DELTA.6-desaturase may be utilized, for example, in the conversion of linoleic acid to .gamma.-linolenic acid and in the conversion of .alpha.-linolenic acid stearidonic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.

La présente invention concerne l'identification de gènes impliqués dans la désaturation d'acides gras polyinsaturés en position carbone 6 (c'est-à-dire, ".DELTA.6-désaturase"). Plus particulièrement, la .DELTA.6-désaturase peut être utilisée, par exemple, dans la conversion d'acide linoléique en acide linolénique .gamma. et dans la conversion d'acide linolénique .alpha. en acide stéaridonique. Les acides gras polyinsaturés produits au moyen de cette enzyme peuvent être ajoutés dans des compositions pharmaceutiques, des compositions nutritionnelles, des aliments pour animaux ainsi que d'autres produits tels que des cosmétiques.

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