A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07H 19/00 (2006.01) C12N 9/02 (2006.01) C12N 15/00 (2006.01) C12P 7/62 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2346006
Novel human DNA sequences that encode the gene CYB5RP, a delta 6 fatty acid desaturase, are provided. Provided are genomic CYB5RP DNA as well as cDNA that encodes the CYB5RP protein. Also provided is CYB5RP protein encoded by the novel DNA sequences. Methods of expressing CYB5RP protein in recombinant systems are provided. Also provided are CYB5RP methods that identify activators and inhibitors of CYB5RP protein.
L'invention porte sur de nouvelles séquences d'ADN humain qui codent le gène CYB5RP et sur une désaturase d'acide gras delta 6. L'invention porte également sur l'ADN génomique CYB5RP, ainsi que sur l'ADNc qui code la protéine CYB5RP. L'invention porte, de plus, sur une protéine CYB5RP codée par les nouvelles séquences d'ADN, sur des procédés d'expression de la protéine CYB5RP dans des systèmes de recombinaison, ainsi que sur des procédés CYB5RP qui identifient les activateurs et les inhibiteurs de la protéine CYB5RP.
Caskey C. Thomas
Petrukhin Konstantin
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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