.delta.9 tetrahydrocannabinol (.delta.9 thc) solution...

A - Human Necessities – 61 – K

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A61K 31/352 (2006.01) A61K 9/00 (2006.01) A61K 9/12 (2006.01) A61K 9/72 (2006.01) A61M 11/00 (2006.01)

Patent

CA 2344637

The present invention provides therapeutic formulations for solutions of .DELTA.9-tetrahydraaannabinol (.DELTA.9 THC) to be delivered by metered dose inhalers. The formulations, which utilize non-CFC propellants, provide a stable aerosol-deliverable source of .DELTA.9 THC for the treatment of various medical conditions, such as: nausea and vomiting associated with chemotherapy; muscle spasticity; pain; anorexia associated with AIDS wasting syndrome; epilepsy; glaucoma; bronchial asthma; and mood disorders.

L'invention concerne des formulations thérapeutiques de solutions de DELTA <9>-tétrahydrocannabinol ( DELTA <9>THC) destinées à être délivrées par des aérosols-doseurs. Ces formulations, qui utilisent des propulseurs autres que les CFC, constituent une source stable, pouvant être délivrée sous forme d'aérosol, de DELTA <9>THC. Elles permettent de traiter divers états pathologiques, tels que les nausées et les vomissements associés à la chimiothérapie; la spasticité musculaire, les douleurs et l'anorexie associées au syndrome d'amaigrissement du sida; l'épilepsie, le glaucome, l'asthme bronchique et les troubles de l'humeur.

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