Delta _-ll-f28249 compounds

Details Delta _-ll-f28249 compounds Delta _-ll-f28249 compounds

C - Chemistry, Metallurgy

07

D

167/202, 260/233

C07D 493/22 (2006.01) A01N 43/90 (2006.01) A01N 49/00 (2006.01) A23K 1/17 (2006.01) A61K 31/365 (2006.01) C07H 19/01 (2006.01)

Patent

CA 1303035

30,402-00 .DELTA.23-LL-F28249 COMPOUNDS ABSTRACT OF THE INVENTION The present invention relates to novel deriva- tives of LL-F28249 compounds wherein the 23-hydroxy group is eliminated to introduce a double bond at the 23,24 position. These resulting derivatives are .DELTA.23-LL-F28249 compounds. These LL-F28249 precursor compounds prefera- bly are derived via a controlled microbiological fermen- tation of Streptomyces cyaneogriseus subsp. noncyanogenus having deposit accession number NRRL 15773. The novel derivatives of the present invention possess activity as anthelmintic, ectoparasitic, insecticidal, acaricidal and nematicidal agents. They also are useful in areas of human and animal health and in agricultural crops.

546562

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