Demineralized bone matrix compositions and methods

Details Demineralized bone matrix compositions and methods Demineralized bone matrix compositions and methods

A - Human Necessities

61

L

A61L 27/36 (2006.01) A61L 27/50 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2702499

Bone matrix compositions and, more specifically, demineralized bone matrix (DBM) having increased osteoinductive capacity and methods for its production are provided. Specifically, DBM derived from cortical bone from the periosteal layer of bone are provided. Compositions comprising a disproportionate amount of DBM prepared from bone derived from the periosteal and/or middle layer of bone are provided. Preparations of and methods of use of periosteal DBM compositions are disclosed.

L'invention a pour objet des compositions de matrice osseuse et, plus spécifiquement, de matrice osseuse déminéralisée (DBM) ayant une capacité ostéoinductrice et des procédés pour leur fabrication. Plus spécifiquement, l'invention concerne une DBM dérivée à partir d'os cortical à partir de la couche périostique de l'os. L'invention concerne également des compositions comprenant une quantité disproportionnée de DBM préparée à partir d'os dérivé de la couche périostique et/ou intermédiaire de l'os. L'invention concerne en outre des préparations et des procédés d'utilisation de compositions de BDM périostique.

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