Denatured albumin complexes for radioscintigraphic imaging...

Details Denatured albumin complexes for radioscintigraphic imaging... Denatured albumin complexes for radioscintigraphic imaging...

A - Human Necessities

61

K

167/48

A61K 49/02 (1980.01)

Patent

CA 1112163

ABSTRACT Small sized material (less than 0.2 µm, preferably less than 0.1 µm) comprising a complex of (1) denatured albumin, particularly human serum albumin and (2) a metal reducing agent, particularly a stannous reducing agent, preferably formed in the presence of a stabilizing ligand, which complex, when labelled with technetium-99m, provides an excellent agent for imaging or otherwise evaluating reticuloendothelial systems (RES) and/or lymphatic system; methods of making and using the same; a complex (physical or chemical) of technetium-99m with such materials and methods of using such latter complex.

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