Dendritic cell modulatory molecule

Details Dendritic cell modulatory molecule Dendritic cell modulatory molecule

C - Chemistry, Metallurgy

07

K

C07K 14/435 (2006.01) A61K 48/00 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) C07K 16/00 (2006.01) C12N 5/00 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2737212

The present invention provides a dendritic cell modulatory molecule which modulates, and preferable inhibits, the differentiation and maturation of mammalian dendritic cells The invention also provides pharmaceutical compositions comprising the dendritic cell modulatory molecule and homologues and active fragments thereof, antibodies thereto and methods of treatment and screening methods which utilise such molecules.

La présente invention concerne une molécule modulatrice des cellules dendritiques, qui se révèle capable de moduler et, de préférence, d'inhiber, la différentiation et la maturation des cellules dendritiques de mammifère. L'invention concerne également des compositions pharmaceutiques comprenant cette molécule modulatrice des cellules dendritiques, ainsi que des homologues et des fragments actifs de celle-ci, des anticorps dirigés contre celle-ci et des procédés de traitement et de criblage faisant appel auxdites molécules.

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