Dendritic cells generated using gm-csf and interferon alpha...

Details Dendritic cells generated using gm-csf and interferon alpha... Dendritic cells generated using gm-csf and interferon alpha...

A - Human Necessities

61

K

A61K 39/00 (2006.01) C12N 5/0784 (2010.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2691346

The present invention includes compositions and methods for making a pharmaceutically effective amount of one or more dendritic cells matured by exposure to IFN.alpha. loaded with cancer antigens from cells that are heat shocked and subsequently killed, wherein the one or more IFN.alpha. dendritic cells are under conditions to present the one or more cancer antigens are presented within the context of autologous MHC.

La présente invention concerne des compositions et des procédés permettant d'élaborer une quantité pharmaceutiquement efficace d'une ou de plusieurs cellules dendritiques amenées à maturité par une exposition à l'interféron IFNa et chargées d'antigènes de cancer issus de cellules qui ont subi un choc thermique et ont été subséquemment inhibées, ladite ou lesdites cellules dendritiques IFNa, dans des conditions de présentation du ou des antigènes de cancer, étant reprises dans le contexte du complexe majeur d'histocompatibilité (MHC) autologue.

Affiliated with

Also associated with

Rating

Dendritic cells generated using gm-csf and interferon alpha... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dendritic cells generated using gm-csf and interferon alpha..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dendritic cells generated using gm-csf and interferon alpha... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2051377