Dengue serotype 2 attenuated strain

Details Dengue serotype 2 attenuated strain Dengue serotype 2 attenuated strain

C - Chemistry, Metallurgy

12

N

C12N 7/08 (2006.01) A61K 39/12 (2006.01) C07K 14/18 (2006.01) C12N 15/40 (2006.01)

Patent

CA 2611954

The invention relates to live attenuated VDV2 (VERO-Derived Vaccine Dengue serotype 2) strains which have been derived from the wild-type dengue-2 strain 16681 by passaging on PDK and Vero cells. The invention further relates to a vaccine composition which comprises a VDV2 strain.

La présente invention concerne des souches vivantes du VDV2 atténué (sérotype dengue 2 du vaccin provenant de cellules VERO), lesquelles ont été obtenues à partir de la souche dengue 2 de type sauvage 16681 par repiquage sur PDK et sur des cellules Vero. Cette invention concerne également une composition de vaccin comprenant une souche VDV2.

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