Dental composition for hypersensitive teeth

A - Human Necessities – 61 – K

Patent

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Details

A61K 8/19 (2006.01) A61K 6/00 (2006.01) A61K 8/81 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2420154

A composition for the treatment of sensitive teeth comprising a suitable carrier and a desensitizing amount of: a) at least one tubule blocking agent, preferably a combination of two such agents; and b) a nerve desensitizing agent selected from the group consisting of at least one potassium salt, at least one strontium salt, and mixtures thereof, wherein the tubule blocking agent deposits or swells upon the dentinal surface and/or precipitates within the dentinal tubules, retaining a higher concentration of the nerve desensitizing agent at the exposed dentinal surface and within the dentinal tubules. The compositions may further contain a source of physiologically acceptable fluoride ion, such as stannous fluoride. Also disclosed are methods of using the subject compositions in the treatment of sensitive teeth.

L'invention concerne une composition destinée au traitement de dents sensibles, comprenant un excipient approprié et une quantité désensibilisante de : a) au moins un agent de blocage tubulé, de préférence, une combinaison de deux agents de ce type ; et b) un agent de désensibilisation du nerf, choisi dans le groupe comprenant au moins un sel de potassium, au moins un sel de strontium, et des mélanges de ceux-ci. L'agent de blocage tubulé se dépose ou gonfle sur la surface de la dentine et/ou précipite dans les tubules de la dentine, tout en retenant une concentration élevée d'agent de désensibilisation du nerf sur la surface exposée de la dentine et à l'intérieur des tubules de la dentine. Les compositions peuvent contenir en outre une source d'ions fluorure physiologiquement acceptable, par exemple de fluorure stanneux. L'invention concerne également des méthodes d'utilisation desdites compositions pour le traitement des dents sensibles.

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