Dentifrice composition

A - Human Necessities – 61 – K

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167/318.1

A61K 8/24 (2006.01) A61K 8/55 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 1183459

Abstract of the Disclosure A dentifrice composition, which provides improved soluble fluorine retention, consisting essentially of a non- toxic amount of a water-soluble monofluorophosphate, about 20 - 99% by weight of a polishing material consisting essential- ly of a calcium salt, at least about 50% by weight of the said calcium salt being dicalcium phosphate and about 0.5 - 5% by weight of a water-soluble surface active material consisting essentially of a non-cationic surface active agent, the said non-cationic surface active agent containing an anionic phosphate ester mixture in an amount of at least about 0.1% by weight of the said dentifrice, the said anionic phosphate ester mixture being a mixture of an anionic phosphate monoester of the formula Image and anionic phosphate diester of the formula Image wherein R represents an alkyl group of 10 - 20 carbon atoms, n is an integer from 1 to 6 and M represents a member selected from the group consisting of a hydrogen atom or an alkali metal cation or an ammonium group. The improved soluble fluorine retention is obtained by the presence of the anionic phosphate mono- and di-esters.

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