Deoxy paclitaxels

Details Deoxy paclitaxels Deoxy paclitaxels

C - Chemistry, Metallurgy

07

D

C07D 407/12 (2006.01) A61K 31/335 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) C07C 233/82 (2006.01) C07C 271/22 (2006.01) C07D 305/14 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07F 7/18 (2006.01) C07F 9/655 (2006.01) C07F 9/6558 (2006.01) H01L 21/48 (2006.01)

Patent

CA 2100808

ABSTRACT Image I in which R1 is -CORZ in which RZ is RO- or R; Rg is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, or a radical of the formula -W-Rx in which W is a bond, C2-6 alkenediyl, or -(CH2)t-, in which t is one to six; and Rx is naphthyl, phenyl, or heteroaryl, and furthermore Rx can be optionally substituted with one to three same or different C1-6 alkyl, C1-6 alkoxy, halogen or -CF3 groups; R2 is -OCOR, H, OH, -OR, -OSO2R, -OCONRoR, -OCONHR, -OCOO(CH2),R, or -OCOOR; and R and Ro are independently C1-6 alkyl, C2-6 alkenyl, C3-6 cycloalkyl, C2-6 alkynyl, or phenyl, optionally substituted with one to three same or different C1-6 alkyl, C1-6 alkoxy, halogen or -CF3 groups. Further provided by this invention are pharmaceutical formulations and intermediates for the the preparation of deoxy taxols of formula I. A method of treating mammalian tumors using a compound of formula I is also provided.

Affiliated with

Also associated with

Rating

Deoxy paclitaxels does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Deoxy paclitaxels, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Deoxy paclitaxels will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1508045