Deoxyclavulanic acid, salts and esters

C - Chemistry – Metallurgy – 07 – D

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C07D 498/04 (2006.01) A61K 31/43 (2006.01) A61K 31/545 (2006.01) C07D 503/00 (2006.01)

Patent

CA 1074802

A N T I B I O T I C S ABSTRACT OF THE DISCLOSURE The compounds of the formula: Image and salts and esters thereof are useful agents for the treatment of bacterial infections either alone or in combination with a penicillin or cephalosporin derivative. The proceeding compounds may be prepared by the hydrogenation of a compound of the formula: Image wherein R is a hydrogen atom or an acyl group or a salt or ester thereof. - 2 -

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