Deoxyhypusine reagent and peptides

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 1/02 (2006.01) C07C 271/22 (2006.01) C07K 1/06 (2006.01) C07K 1/10 (2006.01) C07K 5/09 (2006.01) C07K 7/02 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2306456

The invention relates to a method and reagent for the synthesis of peptides containing deoxyhypusine, the reagent having formula: (1) wherein: Q1 and Q2 may be the same or different and are amino protective groups, and Q3 is an amino protective group which is orthogonal to Q1 and Q2.

La présente invention concerne un procédé et un réactif utiles pour la synthèse de peptides renfermant de la désoxyhypusine. Le réactif est représenté par la formule (1) dans laquelle Q¿1? et Q¿2?, qui peuvent être identiques ou différents, sont des groupes amino protecteurs, et Q¿3? est un groupe amino protecteur qui est orthogonal à Q¿1? et à Q¿2?.

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