Deoxynojirimycin and d-arabinitol analogs and methods of using

Details Deoxynojirimycin and d-arabinitol analogs and methods of using Deoxynojirimycin and d-arabinitol analogs and methods of using

C - Chemistry, Metallurgy

07

D

C07D 211/40 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) C07D 207/12 (2006.01)

Patent

CA 2652958

Novel imino sugar compounds prepared by a variety of methods are provided. In some cases, the novel imino sugars are deoxynojirimycin analogs. Exemplary methods of preparation include condensation reactions of an aldehyde with a piperidinyl or pyrrolidinyl compound. The imino sugar compounds may be used to inhibit glucosidase.

La présente invention concerne de nouveaux composés imino-sucre préparés par une variété de procédés. Dans certains cas, les nouveaux imino-sucres sont des analogues de désoxynojirimycine. Les procédés de préparation à titre d'exemple comprennent des réactions de condensation d'un aldéhyde avec un composé pipéridinyle ou pyrrolidinyle. Les composés imino-sucre peuvent être utilisés pour inhiber la glucosidase.

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