Deoxynucleoside kinase from insect cells for the synthesis...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/54 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12P 19/30 (2006.01)

Patent

CA 2284101

Recombinant kinase remaining stable during the synthesis of nucleoside monophosphate without the addition of stabilizing SH reagents, without stabilizing proteins and accepting all four natural deoxynucleotides, obtainable from insect cells such as e.g. Drosophila Melanogaster. In addition, the invention concerns DNA sequences, vectors, transformed cells, a method for production of the recombinant kinase as well as its use for preparing nucleoside monophosphates.

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