Depolymerized hexosaminoglucan sulfates endowed with an...

Details Depolymerized hexosaminoglucan sulfates endowed with an... Depolymerized hexosaminoglucan sulfates endowed with an...

C - Chemistry, Metallurgy

08

B

167/199, 260/212

C08B 37/08 (2006.01) C08B 37/00 (2006.01) C08B 37/10 (2006.01)

Patent

CA 1283098

DEPOLYMERIZED HEXOSAMINOGLUCAN SULFATES ENDOWED WITH AN ANTITHROMBOTIC, FIBRINOLYTIC, ANTIINFLAMMATORY ACTIVITY, THEIR PROCESS OF PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS Abstract: The present invention concerns a process for the preparation of oligosaccharides by a controlled chemical depolymerization of natural polysaccharides, such as hepa- rins, heparan sulfates, dermatan sulfates, chondroitinsul- fates, hyaluronic acid, by a radicalic reaction in an aqueous solution, at a temperature ranging between 20° and 70°C, in the presence of a catalyst selected in the group consisting of Cu++, Fe++, Cr+++, Cr2O7-- as well as the resulting oligosaccharides and their related pharmaceuti- cal compositions.

509396

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