Depot formulation comprising ceftiofur and peroxidized...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/48 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 31/415 (2006.01) A61K 31/43 (2006.01) A61K 31/545 (2006.01) A61K 31/65 (2006.01) A61K 45/06 (2006.01) A61K 47/14 (2006.01) A61K 47/44 (2006.01) C07D 501/00 (2006.01) A61K 47/06 (2006.01)

Patent

CA 2416566

A composition comprising crystalline ceftiofur free acid and a liquid carrier, wherein said liquid carrier comprises an unsaturated oil having a peroxide value of between 0.1 and 600 milliequivalents (mEq) of peroxide per 1000 grams of oil. The composition is useful for the sustained release of crystalline ceftiofur free is the treatment of bacterial infections in mammalian animals. Compositions according to the invention have an improved shelf-life and retain the original sustained release properties and performance for extended periods of time.

L'invention concerne une composition renfermant (a) au moins un agent bioactif; et (b) un support liquide modifié. Immédiatement après la préparation de la composition, celle-ci peut être administrée à un hôte, de manière à obtenir une libération prolongée d'au moins un agent bioactif dans celui-ci.

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