Deprotection and purification of oligonucleotides and their...

Details Deprotection and purification of oligonucleotides and their... Deprotection and purification of oligonucleotides and their...

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) C07H 1/02 (2006.01) C07H 21/00 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2492208

Method for synthesis, deprotection, and/or purification of nucleic acid molecules, such as oligonucleotides comprising one or more ribonucleotides. Such nucleic acid molecules include siRNA, dsRNA, ribozymes, antisense, and aptamers.

L'invention concerne un procédé pour la synthèse, la déprotection, et/ou la purification de molécules d'acides nucléiques, par exemple des oligonucléotides renfermant un ou plusieurs ribonucléotides. Lesdites molécules d'acides nucléiques comportent de l'ARNsi, de l'ARNds, des ribozymes, des antisens et des aptamères.

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