Deprotection and purification of oligonucleotides and their...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/00 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2593583

Method for synthesis, deprotection, and/or purification of nucleic acid molecules, such as oligonucleotides comprising one or more ribonucleotides. Such nucleic acid molecules include siRNA, dsRNA, ribozymes, antisense, and aptamers.

L'invention concerne un procédé utilisé dans la synthèse, la déprotection, et/ou la purification de molécules d'acides nucléiques, tels que des oligonucléotides comprenant un ou plusieurs ribonucléotides. Lesdites molécules d'acide nucléique comprennent de l'ARNsi, de l'ARNds, des ribozymes, des éléments antisens et des aptamères.

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