C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
167/37, 195/1.12
C07H 21/00 (2006.01) C07J 43/00 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 1242657
ABSTRACT Derivatised nucleic acid sequences The present invention provides derivatised nucleic acid sequences with one or more structural elements of the general formula:- X - A- M (I) wherein X is the group ? N- or ? N-R-N'H-, in which the nitrogen atom is the amine nitrogen atom of a nuclein base and R is a straight-chained or branched lower alkylene radical which can be interrupted by heteroatoms, A is a bifunctional bridge member and M is a component of an immunological reaction. The present invention also provides processes for the preparation of these derivatised nucleic acid sequences and a process for the determination of nucleic acids and nucleic acid sequences.
489275
Graf Hermann
Lenz Helmut
Boehringer Mannheim G.m.b.h.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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