Derivative of cephalosporanic acid and pharmaceutical...

C - Chemistry – Metallurgy – 07 – D

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C07D 501/57 (2006.01) A61K 31/545 (2006.01)

Patent

CA 1200238

TITLE OF THE INVENTION: DERIVATIVE OF CEPHALOSPORANIC ACID AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ABSTRACT OF THE INVENTION: Disclosed herein are a derivative of a substituted cephalosporanic acid, represented by the formula (I): Image (I) wherein p is 0, 1 or 2 and R1 represents a hydrogen atom, a hydrox- yl group, a carbamoyl group, an alkyl group having 1 to 4 carbon atoms or -(CONH)m(CH2)n-COOH wherein m is 0 or 1; n is 0, 1 or 2 and the carboxyl group may have been converted to the salt or the ester thereof, and an antibiotic comprising a derivative of substituted cephalosporanic acid represented by the formula (I).

444435

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