Derivatives...

A - Human Necessities – 61 – K

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A61K 31/4188 (2006.01) A61P 29/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2603214

Derivatives of 6,7-dihydro-5H-imidazo[l,2-<2]imidazole-3-sulfonyt]-azetidine- carboxylic acids, esters and amides which exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.

La présente invention concerne des dérivés d'amides, esters et acides [6,7-dihydro-5H-imidazo [1,2-alpha]imidazole-3-sulfonyl]-azétédino-carboxyliques qui présentent une bonne activité anti-inflammatoire par interaction avec les molécules d'adhésion cellulaires (CAM) et les leucointégrines, et ocnviennent donc pour le traitement d'affections inflammatoires.

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