Derivatives 2-benzamido-5-nitro-thiazoles

Details Derivatives 2-benzamido-5-nitro-thiazoles Derivatives 2-benzamido-5-nitro-thiazoles

C - Chemistry, Metallurgy

07

D

260/310.5

C07D 277/58 (2006.01) C07D 277/46 (2006.01)

Patent

CA 1041519

ABSTRACT OF THE DISCLOSURE This invention relates to a process for preparing new derivatives of 2-benzamido-5-nitro-thiazole which can be used as parasiticides, fungistatic agents and molluscicidal agents. The new derivatives may be represented by the following formula: Image (I), in which at least one of the symbols R1, R2, R3, R4 and R5 represents an acyloxy group, whereas the remaining symbols represent hydrogen or one of said remaining symbols represents an alkoxy group or a halogen atom. The preferred acyloxy groups are the acetyl and propionyl groups, whereas the preferred alkoxy group is the methoxy group. The new compounds of formula I are prepared by reacting 2-amino-5-nitrothiazole of the formula: Image (II) with a benzoyl halide of the formula: Image (III) in which Hal represents a halogen atom, preferably a chlorine atom, whereas R1, R2, R3, R4 and R5 have the above meanings, in the presence of triethylamine.

205468

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