C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/308.3
C07D 285/10 (2006.01)
Patent
CA 1248962
ABSTRACT Novel intermediates useful in the processes of making histamine H2-antagonists of the formula Image I wherein p is 1 or 2; R1 is hydroxy, amino, substituted amino or a 5- to 7-membered fully saturated nitrogen-containing heterocyclic ring attached via its nitrogen atom; m is an integer of from 0 to 2; n is an integer of from 2 to 4; Z is sulfur, oxygen or methylene; and A is an optionally substituted phenyl, imidazolyl, thiazolyl, isothiazolyl, oxazolyl, isoxazolyl, triazolyl, thiadiazolyl, isothiazolyl, oxazolyl, isoxazolyl, triazolyl, thiadiazolyl, oxadiazolyl, furyl, thienyl or pyridyl ring; are disclosed. Also disclosed are processes for their preparation.
431960
Algieri Aldo A.
Crenshaw Ronnie R.
Bristol-Myers Company
Gowling Lafleur Henderson Llp
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