Derivatives of 1,3-benzodioxole and the preparation thereof

Details Derivatives of 1,3-benzodioxole and the preparation thereof Derivatives of 1,3-benzodioxole and the preparation thereof

C - Chemistry, Metallurgy

07

D

260/351.1, 260/3

C07D 413/12 (2006.01) C07D 317/46 (2006.01) C07D 317/58 (2006.01) C07D 405/12 (2006.01)

Patent

CA 1042893

ABSTRACT OF THE DISCLOSURE New derivatives of 1,3-benzodioxole and their acid addition salts are provided and their preparation: the deriva- tives have the formula:- Image in which Z represents a Image or Image group, R1 and R2 which may be identical or different represent each a lower alkyl group containing 1 to 4 carbon atoms, R1 may also represents hydrogen, and R1 and R2 may also form with the attached nitrogen atom a nitrogenous heterocyclic ring, selected among the piperidino, pyrrolidino and morpholino rings, n is equal to 1 or 2, when Z represents a -CH2- or Image group whereas n is equal to 2 or 3, when Z represents a Image group: the new derivatives are active in the treatment of heart arrhythmia and vascular heart diseases.

214814

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