Derivatives of 1-phenyl-1-propanol

Details Derivatives of 1-phenyl-1-propanol Derivatives of 1-phenyl-1-propanol

C - Chemistry, Metallurgy

07

D

260/324, 260/602

C07D 207/27 (2006.01) C07C 317/32 (2006.01) C07C 323/19 (2006.01) C07C 323/32 (2006.01) C07D 303/34 (2006.01)

Patent

CA 1127164

ABSTRACT A derivative of 1-phenyl-1-propanol of the general formula I : Image (I) wherein : (a) R1 represents hydrogen, an linear or ramified alkylthio (c1-C3), linear or ramified alkylsulfinyl (C1-C3), li- near or ramified alkylsulfonyl (C1-C3) or mercapto ra- dical ; (b) R2 represents : b-1 a hydroxy radical ; b-2 an oxo-2-pyrrolidinyl-1 radical which may bc subs- tituted by a hydroxy group ; b-3 a NHR3 radical wherein R3 represents : - hydrogen - a linear or ramified alkyl (C6-C16) radical or a linear alkyl (C2-C4) radical substituted by a phe- nyl or phenoxy group, with the proviso that R1 is not an alkylthio radical - a linear or ramified alkyl (C1-C7) radical substi- tuted by a lower carboxy or carbalkoxy (C1-C3) group in the position ; as well as non toxic and pharmaceutically acceptable salts and esters of these derivatives.

331500

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