C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/08 (2006.01) A61K 31/70 (2006.01)
Patent
CA 2183049
The invention relates to derivatives of 12,13-epoxy-tylosin, the novel semisynthetic antibiotics from the tylosin group and the methods for their preparation. According to this invention hydrogenation followed by oximation of 12,13-epoxy-tylosin derivatives yieldsthe following tylosin derivatives: 10,11-dihydro-12,13-epoxy, respectively 10,11-dihydro- 12,13-epoxy oxime. Direct oximation of 12,13-epoxy tylosin derivative gives 12,13-epoxy oxime derivatives of tylosin.
Lopotar Nevenka
Narandja Amalija
Dioni Cko Drustvo Pliva Farmaceutska Kemijska Prehrambena I. Kozmeticka Industrija
Lopotar Nevenka
Narandja Amalija
Ogilvy Renault
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