Derivatives of 2-amino-6, 7-dihydroxytetrahydro- naphthalene...

Details Derivatives of 2-amino-6, 7-dihydroxytetrahydro- naphthalene... Derivatives of 2-amino-6, 7-dihydroxytetrahydro- naphthalene...

C - Chemistry, Metallurgy

07

C

260/489.7, 260/5

C07C 91/30 (1980.01) C07C 93/26 (1980.01)

Patent

CA 1150302

ABSTRACT OF THE DISCLOSURE This invention provides derivatives of 2-amino-6,7-dihy- droxytetrahydronaphthalene (ADTN) represented by the formula Image wherein R is OH, alkyloxy, hydroxyalkyl or acyloxy, and R' is an arylalkyl where the aryl group is benzyl, substituted benzyl, phenyl or substituted phenyl and the alkyl group is a straight or branched chain alkyl having one to twenty carbon atoms; and the pharmaceutically acceptable salts thereof. These derivatives of 2-amino-6,7-dihydroxytetrahydro- naphthalene are useful as inotropes.

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