Derivatives of 2-carboxymethylthio- benzothiazole and...

Details Derivatives of 2-carboxymethylthio- benzothiazole and... Derivatives of 2-carboxymethylthio- benzothiazole and...

C - Chemistry, Metallurgy

07

D

260/309, 260/277

C07D 417/12 (2006.01) C07D 213/32 (2006.01) C07D 277/74 (2006.01)

Patent

CA 1157024

ABSTRACT OF THE DISCLOSURE Benzothiazole derivatives of the formula I Image I wherein R1 is H or CH3; R2 is phenyl, tolyl, xytyl or pyridyl; R3 is OH, alkoxy of 1 - 4 C atoms or -NHCH2CH2OH; and R4 is H, Cl, Br, OH or alkoxy of 1 - 4 C atoms, and physiologically acceptable salts thereof, have valuable pharmacological properties, e.g., antiarterioschlerotic action, and a reducing action on the lipid level, namely, on the cholesterol level, and on the triglyceride level.

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