Derivatives of 2-oxo-alkyl-1-piperazin-2-one, preparation...

Details Derivatives of 2-oxo-alkyl-1-piperazin-2-one, preparation... Derivatives of 2-oxo-alkyl-1-piperazin-2-one, preparation...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/496 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2726666

The invention relates to derivatives of 4-{2-[phenyl-3,6- dihydro-pyridin-1-yl]-2-oxo-alkyl}-1-piperazin-2-one and 4-{2-[phenyl-2,5-dihydro-pyrrol-1- yl]-2-oxo-alkyl}-1 -piperazin-2-one having general formula (I), wherein: A, B, m, R3 and n are as defined in claim 1. The invention also relates to the preparation thereof and to the therapeutic use of same.

La présente invention a pour objet des dérivés de dérivés de 4-{2-[phényl-3,6- dihydro-pyridin-1 -yl]-2-oxo- alkyl}-1 -pipérazin-2-one et 4-{2-[phényl-2,5-dihydro-pyrrol-1 - yl]-2-oxo- alkyl}-1 -pipérazin-2-one de formule générale (I) dans laquelle A, B, m, R3 et n sont définis comme en revendication 1, leur préparation et leur application en thérapeutique.

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